Neurophysiology of orgasm

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The neurophysiology of the sexual cycle

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The Neurophysiology of Orgasm

Despite decades of research, the neurophysiology of orgasm remains unknown. Animal models with the urethrogenital reflex in rats and facial expressions of orgasm in macaques have provided remarkable contributions, but the models can only explain a part of the overall perceptual experience of orgasm in humans. Human studies on the other hand have mostly focused on subjective reports, and while a few instruments have been developed but seldom used , the distinction between orgasm and intense sexual pleasure has not always been demonstrated. Recent advances in functional imagery have further contributed to our understanding of orgasm, but a final comprehensive model bringing together all the findings and explaining the neurophysiology of orgasm is still lacking. This paper reviews the literature on orgasm, from animal studies to human data, including those from men and women with spinal cord lesions who offer a natural experimental model to study climax.
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How do orgasms affect the brain? Study investigates

Try out PMC Labs and tell us what you think. Learn More. Orgasm is one of the most intense pleasures attainable to an organism, yet its underlying mechanisms remain poorly understood. On the basis of existing literatures, this article introduces a novel mechanistic model of sexual stimulation and orgasm.
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When it comes to the human orgasm, research has primarily focused on how this intense feeling of sexual pleasure has evolved. In a new study, one researcher has delved into a relatively understudied area of human climax: how orgasms affect the brain. Described as a powerful, pleasurable release of accumulated sexual tension, the orgasm is perceived as the epitome of sexual pleasure for both men and women. During orgasm, an individual may experience a rise in blood pressure , an increased heart rate, heavy breathing, and rhythmic muscular contractions. But while the signs and sensations of an orgasm might be clear, the underlying mechanisms of this sexual response — particularly its neurophysiological effects — remain uncertain.
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